His then wife Lori Anne Allison introduced him to Nicolas Cage, the man who advised him to try acting. This led him to take on various roles which shot him to fame, like the undercover cop Tommy Hanson in the popular TV series 21 Jump Street. This role made him a teen idol, an image very different from the eclectic artist image he has now. We all know of his fateful meeting with Tim Burton with Edward Scissorhands which marks the beginning of his acting career as we know it.
Speaking of Tim Burton: Producer Scott Rudin once said “Basically Johnny Depp is playing Tim Burton in all his movies,” which Depp seems to agree with even if Burton objected to the comment.